COMPOSITION. Purified protein derivative of the adapted mycobacteria of M. scrofulaceum and M. intracellular type, which contains sodium chloride, Glycerin and Phenol at a concentration ratio 7,0 0,5 after dissolution in the dissolvent.
PHARMACEUTICAL FORM. Dry lamina or in the form of a tablet of white up to light-grey or light-yellow colour mass which is available in 10 ml glass vial occluded with the rubber bung and sealed with the aluminium cap.
Different vials contain 13500 and 33750 units of drug activity.
INDICATION. Simultaneous allergic test is used for the research of cattle tuberculosis disease (if any) in animals with tuberculin sensibilization by atypical mycobacteria, and with the purpose of revealing the causes of tuberculin test origination in mammals, and making cattle tuberculosis diagnosis, and for the control of animals well-being concerning tuberculosis disease.
VACCINATION SCHEDULE AND DOSAGE. Tuberculosis research is administered via intracutaneous allergic skin test.
Intracutaneous allergic skin test consists of separate introduction of 2 allergens into the animal simultaneously:
– 1) dry purified tuberculin (PPD) for mammals in standard solution and 2) dry purified allergen from atypical mycobacteria (AAM), in the dissolvent of mycobacterial allergens;
1.1 Tuberculin and AAM is administered:
– in cows and young animals at 6 months of age symmetrically into the skin high up on the neck or subcaudal fold (tuberculin on the left, and AAM on his right), or in case of necessity into subcaudal fold;
– in young animals at 6 months of age into the skin high up on the neck or middle part of blade bone;
– in bulls into subcaudal fold
1.2 The influence of the test is administered in 72 hours via palpation after tuberculin injection and AAM by measuring the skin fold of the injection site and around the injection site with cutimetre.
Doses of allergens for cattle: tuberculin – 5000 international units, and AAM – 675 units of drug activity in 0,1 ml of the dissolvent.
VACCINE SHELF-LIFE. 2 years from the date of its manufacturing.
CONDITIONS OF STORAGE. The vaccine is stored in the manufacturer’s packaging in a dry, dark place at temperature 2-8 0 С.
PACKAGING. The vaccine is available in 10 ml vials which separately contain 13500 and 33750 of dry allergen and which should be dissolved accordingly in 2 and 5 ml mycobacterial allergen dissolvent before usage.